Entos Pharmaceuticals Inc.
$128,600.00 CAD
≈ 20 months of average Canadian pay
- Department
- National Research Council Canada
- Recipient country
- Canada
- Fiscal year
- 2018-2019
- Agreement period
- October 1, 2018 – September 30, 2019
- Reference
- nrc-cnrc:172-2018-2019-Q3-913718
Published purpose
The goal of this project is to establish a method to synthesize Fusogenix DNA lipid nanoparticles using a single step manufacturing process. To achieve this, we will evaluate a number of methods to incorporate our fusogenic proteins into lipid nanoparticles using the Precision Nanosystems microfluidic platform. We expect that by pre-formulating one of the lipid components with fusogenic protein, we may be able to reduce the manufacturing to a single step compared to the current 2 step process. This will allow us to significantly improve our encapsulation efficiency and simplify our manufacturing process as we move to the clinic.
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Imported August 3, 2026 from open.canada.ca Grants & Contributions