The Royal Institution for the Advancement of Learning/McGill University
$25,000.00 CAD
≈ 4 months of average Canadian pay
- Department
- National Research Council Canada
- Recipient country
- Canada
- Fiscal year
- 2018-2019
- Agreement period
- March 15, 2019 – March 31, 2020
- Reference
- nrc-cnrc:172-2018-2019-Q4-00036
Published purpose
We will use Cryo-Electron Microscopy (McGill University) and Hydrogen-Deuterium Exchange Mass Spectrometry to study the mechanism by which antibodies bind to Insulin-like Growth Factor 1 Receptor (IGF1R) and cross the blood-brain barrier. Sophisticated models of receptor/antibody interactions will be constructed and used to decipher the molecular events that initiate crossing.
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Imported July 30, 2026 from open.canada.ca Grants & Contributions