Université Laval

$100,000.00 CAD

≈ 16 months of average Canadian pay
Department
National Research Council Canada
Program
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Recipient country
Canada
Fiscal year
2020-2021
Agreement period
September 17, 2020 – September 17, 2022
Reference
nrc-cnrc:172-2020-2021-Q2-956909

Published purpose

This Project seeks to produce recombinant St1Cas9 and variants and test their efficiency both in vitro and in vivo. These recombinant gene editing tools will become part of the toolkit the NRC-CGT Program aims to build to facilitate multiplex combinatorial gene editing in induced pluripotent stem cells (iPSCs) and immune cells. Along with the production of SpCas9, MAD7, and potentially Cas12a, the production of St1Cas9 and variants will broaden target flexibility and help to accelerate innovation and discovery cycles in engineered cell and gene therapies.

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