Institut National de la Recherche Scientifique

$25,000.00 CAD

≈ 4 months of average Canadian pay
Department
National Research Council Canada
Program
Collaborative Science, Technology and Innovation Program – Ideation Fund
Recipient country
Canada
Fiscal year
2021-2022
Agreement period
August 5, 2021 – September 30, 2022
Reference
nrc-cnrc:172-2021-2022-Q2-967265

Published purpose

RNAs were long believed not to be glycosylated. However, a recent report described the discovery of glycosylated RNA species, including Y5 RNA, in mammalian cells. The functional significance of these newly identified molecules is unknown. We propose to investigate the effect glycosylation has on the response of cells in culture to two different RNAs (Poly I:C and Y5 RNA). This work could have an impact in the field of vaccine adjuvants.

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