Pacylex Pharmaceuticals Inc
$187,700.00 CAD
≈ 2 Canadians' average pay for a year
- Department
- National Research Council Canada
- Recipient country
- Canada
- Fiscal year
- 2021-2022
- Agreement period
- November 1, 2021 – December 31, 2022
- Reference
- nrc-cnrc:172-2021-2022-Q3-980902
Published purpose
This project will enable the creation and optimization of deuterated PCLX-001 analogues designed to improve the therapeutic index of PCLX-001 and bring to market an improved compound: deuterated variants of drugs can resist metabolic degradation in vivo which can increase the half-life in a patient and, consequently, both i) enable a lower dose while maintaining a similar efficacy, and ii) decrease Cmax based side-effects.
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