BC Cancer, part of the Provincial Health Services Authority

$110,220.00 CAD

≈ 17 months of average Canadian pay
Department
National Research Council Canada
Program
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Recipient country
Canada
Fiscal year
2020-2021
Agreement period
July 13, 2020 – February 2, 2023
Reference
nrc-cnrc:172-2022-2023-Q2-953930

Published purpose

The main goal of this work is to create a made-in-Canada clinical ready approach for genome editing of CAR-T for cancer immunotherapy. The project aims to enhance the potency of single-domain antibody (sdAb) targeted CAR-Ts being developed by the Cell and Gene Therapy program, through site specific integration into rationally selected gene loci under conditions that are conducive to GMP CAR-T manufacture.

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